YDR083W

Description : Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1 [Source:SGD;Acc:S000002490]

Gene families : OG_03_0002727 (OF) Phylogenetic Tree(s): OG0002727_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR083W
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AFR95042	No alias	ribosomal RNA-processing protein 8;Hypothetical methyltransferase	0.13	OF
AOA65892	No alias	Ribosomal RNA processing protein 8	0.1	OF
CAG78353	No alias	Ribosomal RNA processing protein 8	0.28	OF
CAK47621	No alias	Hypothetical methyltransferase	0.33	OF
CBF70668	No alias	rRNA processing protein Rrp8, putative	0.28	OF
EAA32828	No alias	Ribosomal RNA processing protein 8	0.14	OF
EDN96425	No alias	Ribosomal RNA processing protein 8	0.2	OF
EGR51903	No alias	Ribosomal RNA processing protein 8	0.26	OF
ESU12219	No alias	Ribosomal RNA processing protein 8	0.09	OF
KHC81869	No alias	ribosomal RNA-processing protein 8;Hypothetical methyltransferase	0.24	OF
MGG_07132T0	No alias	Ribosomal RNA-processing protein 8...	0.25	OF
POW17843	No alias	Ribosomal RNA processing protein 8	0.05	OF
SPAC56F8.09.1	No alias	rRNA methyltransferase Rrp8 (predicted)...	0.12	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005730	nucleolus	IEA	Interproscan
MF	GO:0008168	methyltransferase activity	IEA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007823	RRP8	113	344

External Links

No external refs found!

YDR083W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation