Description : Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation [Source:SGD;Acc:S000002459]
Gene families : OG_03_0002773 (OF) Phylogenetic Tree(s): OG0002773_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR052C | |
Cluster | HCCA: Cluster_18 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF85546 | No alias | G1/S regulator | 0.03 | OF | |
EDN99421 | No alias | Regulatory subunit Dfp1/Him1, central region | 0.03 | OF | |
ESU15865 | No alias | Zinc finger, DBF-type | 0.03 | OF | |
KHC71967 | No alias | regulatory subunit for Cdc7p protein kinase;"Dfp1/Him1,... | 0.03 | OF | |
SPCC550.13.1 | No alias | Hsk1-Dfp1 kinase complex regulatory subunit Dfp1... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003676 | nucleic acid binding | IEA | Interproscan |
MF | GO:0008270 | zinc ion binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |