Description : Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation [Source:SGD;Acc:S000002459]

Gene families : OG_03_0002773 (OF) Phylogenetic Tree(s): OG0002773_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR052C
Cluster HCCA: Cluster_18

Target Alias Description ECC score Gene Family Method Actions
CBF85546 No alias G1/S regulator 0.03 OF
EDN99421 No alias Regulatory subunit Dfp1/Him1, central region 0.03 OF
ESU15865 No alias Zinc finger, DBF-type 0.03 OF
KHC71967 No alias regulatory subunit for Cdc7p protein kinase;"Dfp1/Him1,... 0.03 OF
SPCC550.13.1 No alias Hsk1-Dfp1 kinase complex regulatory subunit Dfp1... 0.05 OF

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan
MF GO:0008270 zinc ion binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR013939 Regulatory_Dfp1/Him1 189 310
IPR006572 Znf_DBF 656 700
No external refs found!