Description : Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human homolog TPI1 causes a rare autosomal disease; human TPI1 can complement yeast null mutant [Source:SGD;Acc:S000002457]

Gene families : OG_03_0003730 (OF) Phylogenetic Tree(s): OG0003730_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR050C
Cluster HCCA: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
AFR95784 No alias triose-phosphate isomerase;Triosephosphate isomerase 0.08 OF
AOA68545 No alias Triosephosphate isomerase 0.18 OF
CAG77830 No alias Triosephosphate isomerase 0.03 OF
CAK42053 No alias triose-phosphate-isomerase tpiA from patent... 0.03 OF
EAA29827 No alias Triosephosphate isomerase 0.03 OF
EAL91271 No alias triosephosphate isomerase 0.05 OF
EAU86629 No alias triosephosphate isomerase 0.02 OF
EGR48570 No alias Triosephosphate isomerase 0.04 OF
ESU12830 No alias triosephosphate isomerase 0.03 OF
KHC79281 No alias triosephosphate isomerase;Triosephosphate isomerase 0.11 OF
MGG_08905T0 No alias Triosephosphate isomerase [Source:UniProtKB/TrEMBL;Acc:G4MVL8] 0.04 OF
SPCC24B10.21.1 No alias triosephosphate isomerase [Source:PomBase;Acc:SPCC24B10.21] 0.04 OF

Type GO Term Name Evidence Source
MF GO:0004807 triose-phosphate isomerase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000652 Triosephosphate_isomerase 6 244
No external refs found!