YDR049W


Description : Component of a Cdc48p-complex involved in protein quality control; exhibits cytosolic and ER-membrane localization, with Cdc48p, during normal growth, and contributes to ER-associated degradation (ERAD) of specific substrates at a step after their ubiquitination; forms a mitochondrially-associated complex with Cdc48p and Npl4p under oxidative stress that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD); conserved in C. elegans and humans [Source:SGD;Acc:S000002456]


Gene families : OG_03_0002908 (OF) Phylogenetic Tree(s): OG0002908_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR049W
Cluster HCCA: Cluster_59

Target Alias Description ECC score Gene Family Method Actions
AOA66470 No alias VLRF1/Vms1 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR041175 VLRF1/Vms1 237 394
No external refs found!