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Description : Component of RQC, which mediates nascent chain degradation; RQC (ribosome quality control complex) is a ribosome-bound complex required for degradation of polypeptides arising from stalled translation; recruits alanine- and threonine-charged tRNA to the A site and directs the elongation of nascent chains independently of mRNA or 40S subunits; monitors translation stress and signals this to Hsf1p [Source:SGD;Acc:S000005930]
Sample enrichment: mid-log,vts1 OE,WT (SPM: 0.26, entropy: 3.88, tau: 0.52)