Description : Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication [Source:SGD;Acc:S000005309]
Sample enrichment: med 35 6aa,WT (SPM: 0.22, entropy: 3.86, tau: 0.4)