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Expression profile for YDL013W (YDL013W)

Description : Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex; role in Ub-mediated degradation of histone variant Cse4p preventing mislocalization to euchromatin; role in proteolysis of spindle positioning protein Kar9p, and DNA repair proteins Rad52p and Rad57p; forms SUMO-dependent nuclear foci, including DNA repair centers; contains a RING domain and two SIM motifs; associates with the centromere; required for maintenance of genome integrity like human ortholog RNF4 [Source:SGD;Acc:S000002171]

Sample enrichment: YPEG,WT (SPM: 0.37, entropy: 3.39, tau: 0.68)
Perturbation specificity: YPEG (SPM: 0.65, entropy: 2.75, tau: 0.67)