Description : Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant [Source:SGD;Acc:S000002290]
Sample enrichment: dmso,WT (SPM: 0.27, entropy: 3.87, tau: 0.56)