Description : Subunit of the DSC ubiquitin ligase complex; golgi-localized RING-finger ubiquitin ligase (E3) involved in sorting polar transmembrane domain containing membrane proteins to multivesicular bodies for delivery to the vacuole; proposed involvement in the quality control of misfolded TMD containing proteins; ortholog of fission yeast dsc1 [Source:SGD;Acc:S000001517]
Sample enrichment: 1n,MATa,NaCl,WT (SPM: 0.29, entropy: 3.54, tau: 0.57)