Description : Ubiquitin-protein ligase (E3); interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001493]
Sample enrichment: gal, 4h + hu 200 mm,WT (SPM: 0.26, entropy: 3.83, tau: 0.53)