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Description : eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade [Source:SGD;Acc:S000001687]
Sample enrichment: YPEG,WT (SPM: 0.43, entropy: 3.1, tau: 0.74)