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Expression profile for YLR215C (YLR215C)

Description : Assembly factor for the eIF2 translation initiation factor complex; regulates translational initiation; conserved residues of this ATP-Grasp protein that bind to ATP-Mg2+ in the pombe ortholog are required for complex assembly in budding yeast; interaction with eIF2 subunit Gcd11p facilitates complex assembly and activity; required for the START transition and timely progression through G2; regulated by nutrient availability; human ortholog complements the yeast mutant [Source:SGD;Acc:S000004205]

Sample enrichment: YPEG,WT (SPM: 0.35, entropy: 3.18, tau: 0.65)
Perturbation specificity: YPEG (SPM: 0.62, entropy: 2.92, tau: 0.63)