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Expression profile for YOL133W (YOL133W)

Description : RING-H2 domain core subunit of multiple ubiquitin ligase complexes; subunit of Skp1-Cullin-F-box (SCF) that tethers the Cdc34p (E2) and Cdc53p (cullin) SCF subunits, and is required for degradation of Gic2p, Far1p, Sic1p and Cln2p; subunit of the Rtt101p-Mms1p-Mms22p ubiquitin ligase that stabilizes replication forks after DNA lesions; subunit of the Cul3p-Elc1p-Ela1p ubiquitin ligase involved in Rpb1p degradation as part of transcription-coupled repair [Source:SGD;Acc:S000005493]

Sample enrichment: ypsorbitol (2.02%),YPD,WT (SPM: 0.28, entropy: 3.76, tau: 0.57)
Perturbation specificity: YPD, sorbitol (SPM: 0.45, entropy: 3.42, tau: 0.47)