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GO:0007186: G protein-coupled receptor signaling pathway (Biological process)

"A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


There are 178 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_25 Saccharomyces cerevisiae 2.86 % 0.001086 0.026554
Cluster_61 Aspergillus nidulans 3.57 % 0.000411 0.029675
Cluster_14 Candida albicans 1.96 % 0.003628 0.047159
Cluster_78 Coprinopsis cinerea 3.06 % 0.000784 0.014192
Cluster_118 Coprinopsis cinerea 3.17 % 0.006126 0.027376
Cluster_48 Coprinopsis cinerea 4.17 % 0.000317 0.002679
Cluster_7 Cryptococcus neoformans 2.63 % 0.0 3.1e-05
Cluster_14 Fusarium graminearum 2.0 % 0.001145 0.024673
Cluster_8 Komagataella phaffii 4.69 % 1.9e-05 0.004577
Cluster_79 Neurospora crassa 3.06 % 5.8e-05 0.006976
Cluster_24 Postia placenta 2.3 % 0.00345 0.041019
Cluster_30 Postia placenta 3.17 % 0.001058 0.023383
Cluster_125 Postia placenta 100.0 % 1.3e-05 8e-05
Cluster_104 Puccinia striiformis 2.99 % 0.001245 0.017022
Cluster_24 Puccinia striiformis 1.32 % 0.006147 0.038456
Cluster_84 Pyricularia oryzae 2.74 % 0.000885 0.019641
Cluster_17 Yarrowia lipolytica 2.61 % 1e-06 0.000239
Sequences (178) (download table)

InterPro Domains

GO Terms

Family Terms