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GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, ISBN:0716720094]


There are 326 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_53 Fusarium graminearum 7.58 % 1e-06 1.7e-05
Cluster_23 Komagataella phaffii 4.0 % 0.00592 0.035522
Cluster_63 Neurospora crassa 4.23 % 0.000244 0.002028
Cluster_11 Neurospora crassa 2.35 % 0.009583 0.042621
Cluster_68 Postia placenta 4.17 % 0.00313 0.015924
Cluster_15 Puccinia striiformis 1.12 % 0.018701 0.037977
Cluster_26 Trichoderma reesei 2.59 % 0.006349 0.043029
Sequences (326) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms