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GO:0017171: serine hydrolase activity (Molecular function)

"Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [Wikipedia:Serine_hydrolase]


There are 641 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_29 Aspergillus fumigatus 7.46 % 4e-06 9.1e-05
Cluster_20 Aspergillus nidulans 2.86 % 0.00263 0.032502
Cluster_81 Aspergillus niger 7.14 % 0.0 1.5e-05
Cluster_64 Aspergillus niger 12.0 % 0.0 0.0
Cluster_36 Candida albicans 3.51 % 0.000148 0.004515
Cluster_21 Coprinopsis cinerea 2.0 % 0.008159 0.027585
Cluster_68 Coprinopsis cinerea 2.82 % 0.000616 0.032235
Cluster_12 Dichomitus squalens 3.32 % 0.000123 0.005323
Cluster_31 Fusarium graminearum 5.0 % 0.002365 0.022545
Cluster_53 Fusarium graminearum 10.61 % 0.0 0.0
Cluster_23 Komagataella phaffii 6.0 % 0.000666 0.012387
Cluster_63 Neurospora crassa 4.23 % 0.00107 0.006421
Cluster_11 Neurospora crassa 7.06 % 0.0 1e-06
Cluster_68 Postia placenta 4.17 % 0.010826 0.028788
Cluster_3 Postia placenta 2.02 % 0.003851 0.017825
Cluster_37 Pyricularia oryzae 5.88 % 4.8e-05 0.000595
Cluster_26 Trichoderma reesei 3.45 % 0.002692 0.021418
Cluster_24 Sclerotinia sclerotiorum 3.23 % 2.6e-05 0.000302
Sequences (641) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms