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GO:0016840: carbon-nitrogen lyase activity (Molecular function)

"Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-]


There are 41 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_55 Aspergillus fumigatus 2.56 % 6.5e-05 0.010573
Cluster_105 Aspergillus nidulans 1.72 % 0.010982 0.046979
Cluster_45 Candida albicans 2.22 % 0.014032 0.047552
Cluster_63 Neurospora crassa 1.41 % 0.013096 0.040996
Cluster_55 Puccinia striiformis 1.89 % 0.013977 0.027604
Sequences (41) (download table)

InterPro Domains

GO Terms

Family Terms