YDL178W

Description : D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase; mitochondrial matrix protein that oxidizes D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate with a minor role in lactate catabolism; located in the mitochondrial matrix [Source:SGD;Acc:S000002337]

Gene families : OG_03_0002340 (OF) Phylogenetic Tree(s): OG0002340_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDL178W
Cluster	HCCA: Cluster_7

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050660	flavin adenine dinucleotide binding	IEA	Interproscan
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR004113	FAD-linked_oxidase_C	277	528
IPR006094	Oxid_FAD_bind_N	103	239

External Links

No external refs found!

YDL178W

Expression Profile

Co-expression Networks

Functional Annotation