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  5. YDL077C

YDL077C


Description : Guanine nucleotide exchange factor for the GTPase Gtr1p; subunit of the HOPS endocytic tethering complex; vacuole membrane protein; functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p; facilitates tethering and promotes membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; component of vacuole-mitochondrion contacts (vCLAMPs) important for lipid transfer between organelles [Source:SGD;Acc:S000002235]


Gene families : OG_03_0003283 (OF) Phylogenetic Tree(s): OG0003283_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDL077C
Cluster HCCA: Cluster_48

Target Alias Description ECC score Gene Family Method Actions
AFR98822 No alias hypothetical protein;Vacuolar sorting protein 39 domain... 0.05 OF
AOA65784 No alias Vacuolar sorting protein 39/Transforming growth factor... 0.05 OF
CAG83012 No alias Vacuolar sorting protein 39/Transforming growth factor... 0.05 OF
CAK48112 No alias Vacuolar sorting protein 39 domain 1 0.04 OF
CBF71321 No alias AvaB protein 0.03 OF
EAA27006 No alias Citron homology (CNH) domain 0.07 OF
EAL86893 No alias vacuolar morphogenesis protein AvaB, putative 0.04 OF
EAU85277 No alias rab guanyl-nucleotide exchange factor 0.05 OF
EDN92326 No alias Citron homology (CNH) domain 0.04 OF
ESU08776 No alias Citron homology (CNH) domain 0.07 OF
KHC81315 No alias hypothetical protein;Vacuolar sorting protein 39 domain... 0.1 OF
MGG_01054T0 No alias Vacuolar morphogenesis protein AvaB... 0.04 OF
SPAC23H4.14.1 No alias guanyl-nucleotide exchange factor, HOPS complex subunit... 0.06 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR019452 VPS39/TGF_beta_rcpt-assoc_1 603 715
IPR019453 VPS39/TGF_beta_rcpt-assoc_2 905 1016
No external refs found!