Description : Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186]
Gene families : OG_03_0002042 (OF) Phylogenetic Tree(s): OG0002042_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDL028C | |
Cluster | HCCA: Cluster_3 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA69230 | No alias | Protein kinase domain | 0.06 | OF | |
CAG77931 | No alias | Protein kinase domain | 0.05 | OF | |
CAK44485 | No alias | Protein kinase domain | 0.05 | OF | |
CBF83734 | No alias | checkpoint protein kinase, putative | 0.03 | OF | |
EAA35935 | No alias | Protein kinase domain | 0.04 | OF | |
EAL92766 | No alias | checkpoint protein kinase, putative | 0.04 | OF | |
EAU86010 | No alias | other/TTK protein kinase | 0.02 | OF | |
EDN96507 | No alias | Protein kinase domain | 0.03 | OF | |
EGR44187 | No alias | Protein kinase domain | 0.04 | OF | |
ESU06419 | No alias | Protein kinase domain | 0.03 | OF | |
MGG_10826T0 | No alias | TTK protein kinase [Source:UniProtKB/TrEMBL;Acc:G4MYX1] | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004672 | protein kinase activity | IEA | Interproscan |
MF | GO:0005524 | ATP binding | IEA | Interproscan |
BP | GO:0006468 | protein phosphorylation | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000719 | Prot_kinase_dom | 440 | 716 |
No external refs found! |