Description : NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases Ypk1p and Ypk2p, dephosphorylation increases catalytic activity; forms a heterodimer with Pnc1p to facilitate its peroxisomal import [Source:SGD;Acc:S000002180]
Gene families : OG_03_0000825 (OF) Phylogenetic Tree(s): OG0000825_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDL022W | |
Cluster | HCCA: Cluster_45 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97947 | No alias | glycerol-3-phosphate dehydrogenase (NAD(... | 0.02 | OF | |
AOA67955 | No alias | Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal | 0.03 | OF | |
CBF71469 | No alias | glycerol-3-phosphate dehydrogenase | 0.02 | OF | |
EAL93121 | No alias | glycerol 3-phosphate dehydrogenase (GfdB), putative | 0.04 | OF | |
KHC73342 | No alias | glycerol-3-phosphate dehydrogenase... | 0.06 | OF | |
POW06830 | No alias | Glycerol-3-phosphate dehydrogenase, NAD-dependent,... | 0.02 | OF | |
SPBC215.05.1 | No alias | glycerol-3-phosphate dehydrogenase Gpd1... | 0.1 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity | IEA | Interproscan |
BP | GO:0005975 | carbohydrate metabolic process | IEA | Interproscan |
MF | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | Interproscan |
BP | GO:0046168 | glycerol-3-phosphate catabolic process | IEA | Interproscan |
MF | GO:0051287 | NAD binding | IEA | Interproscan |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |