YDL022W


Description : NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases Ypk1p and Ypk2p, dephosphorylation increases catalytic activity; forms a heterodimer with Pnc1p to facilitate its peroxisomal import [Source:SGD;Acc:S000002180]


Gene families : OG_03_0000825 (OF) Phylogenetic Tree(s): OG0000825_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDL022W
Cluster HCCA: Cluster_45

Target Alias Description ECC score Gene Family Method Actions
AFR97947 No alias glycerol-3-phosphate dehydrogenase (NAD(... 0.02 OF
AOA67955 No alias Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal 0.03 OF
CBF71469 No alias glycerol-3-phosphate dehydrogenase 0.02 OF
EAL93121 No alias glycerol 3-phosphate dehydrogenase (GfdB), putative 0.04 OF
KHC73342 No alias glycerol-3-phosphate dehydrogenase... 0.06 OF
POW06830 No alias Glycerol-3-phosphate dehydrogenase, NAD-dependent,... 0.02 OF
SPBC215.05.1 No alias glycerol-3-phosphate dehydrogenase Gpd1... 0.1 OF

Type GO Term Name Evidence Source
MF GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity IEA Interproscan
BP GO:0005975 carbohydrate metabolic process IEA Interproscan
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA Interproscan
BP GO:0046168 glycerol-3-phosphate catabolic process IEA Interproscan
MF GO:0051287 NAD binding IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006109 G3P_DH_NAD-dep_C 234 379
IPR011128 G3P_DH_NAD-dep_N 36 201
No external refs found!