YDL015C


Description : Enoyl reductase; catalyzes last step in each cycle of very long chain fatty acid elongation; localizes to ER, highly enriched in a structure marking nuclear-vacuolar junctions; coimmunoprecipitates with elongases Elo2p and Elo3p; protein increases in abundance and relative distribution to ER foci increases upon DNA replication stress; human homolog TECR implicated in nonsyndromic mental retardation, can complement yeast mutant [Source:SGD;Acc:S000002173]


Gene families : OG_03_0003403 (OF) Phylogenetic Tree(s): OG0003403_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDL015C
Cluster HCCA: Cluster_55

Target Alias Description ECC score Gene Family Method Actions
CAG83695 No alias 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 0.03 OF
EAU85246 No alias 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 0.04 OF
EGR50928 No alias 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 0.02 OF
ESU05835 No alias 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 0.03 OF
KHC82894 No alias enoyl reductase;3-oxo-5-alpha-steroid 4-dehydrogenase 0.06 OF
MGG_03250T0 No alias Enoyl reductase TSC13 [Source:UniProtKB/TrEMBL;Acc:G4N9V3] 0.05 OF
SPBC646.07c.1 No alias enoyl reductase (predicted) [Source:PomBase;Acc:SPBC646.07c] 0.1 OF

Type GO Term Name Evidence Source
BP GO:0006629 lipid metabolic process IEA Interproscan
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001104 3-oxo-5_a-steroid_4-DH_C 155 310
No external refs found!