Description : Actin-binding protein of the cortical actin cytoskeleton; important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; inhibits barbed-end actin filament elongation; phosphorylation within its Proline-Rich Regio, mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa) [Source:SGD;Acc:S000000684]
Gene families : OG_03_0000623 (OF) Phylogenetic Tree(s): OG0000623_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YCR088W | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94769 | No alias | hypothetical protein;SH3 domain;Variant SH3... | 0.03 | OF | |
CAG83119 | No alias | SH3 domain | 0.05 | OF | |
CAK38453 | No alias | SH3 domain | 0.03 | OF | |
EGR50809 | No alias | Actin-depolymerising factor homology domain | 0.03 | OF | |
EJF58050 | No alias | Cofilin/tropomyosin-type actin-binding protein | 0.02 | OF | |
ESU06617 | No alias | SH3 domain | 0.02 | OF | |
KHC77583 | No alias | hypothetical protein;SH3 domain;Cofilin/tropomyosin-type... | 0.06 | OF | |
POW00939 | No alias | SH3 domain;SH3 domain;Actin-depolymerising factor homology domain | 0.02 | OF | |
SPAPJ760.02c.1 | No alias | cofilin/tropomyosin family, drebrin ortholog Abp1... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003779 | actin binding | IEA | Interproscan |
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |