Description : GTPase-activating protein, stimulates the GTPase activity of Sar1p; component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat, involved in ER to Golgi transport; substrate of Ubp3/Bre5 complex; ubiquitylated by Ub-ligase Rsp5p; proteasome-mediated degradation of Sec23p is regulated by Cdc48p [Source:SGD;Acc:S000006385]

Gene families : OG_03_0001625 (OF) Phylogenetic Tree(s): OG0001625_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YPR181C
Cluster HCCA: Cluster_39

Target Alias Description ECC score Gene Family Method Actions
AFR97534 No alias protein transporter SEC23;Sec23/Sec24 helical... 0.04 OF
AOA65775 No alias Sec23/Sec24, helical domain 0.08 OF
AOA69531 No alias Zinc finger, Sec23/Sec24-type 0.08 OF
CAG79640 No alias Gelsolin-like domain 0.09 OF
CAK37008 No alias Sec23/Sec24 beta-sandwich domain 0.12 OF
CBF89861 No alias Protein transport protein sec23 0.1 OF
EAA32168 No alias Sec23/Sec24 beta-sandwich 0.15 OF
EAL88052 No alias protein transport protein Sec23, putative 0.07 OF
EAU89573 No alias protein transporter SEC23 0.04 OF
EDN97626 No alias Sec23/Sec24, trunk domain 0.07 OF
EGR45004 No alias Sec23/Sec24 beta-sandwich 0.07 OF
EJF56800 No alias Gelsolin repeat 0.03 OF
ESU07283 No alias transporter SEC23 0.12 OF
KHC76645 No alias protein transporter SEC23;Sec23/Sec24 helical... 0.18 OF
SPCC31H12.07.1 No alias COPII cargo receptor subunit Sec23a (predicted)... 0.05 OF

Type GO Term Name Evidence Source
BP GO:0006886 intracellular protein transport IEA Interproscan
BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IEA Interproscan
MF GO:0008270 zinc ion binding IEA Interproscan
CC GO:0030127 COPII vesicle coat IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007123 Gelsolin-like_dom 637 724
IPR006896 Sec23/24_trunk_dom 120 388
IPR012990 Sec23_24_beta_S 399 510
IPR006895 Znf_Sec23_Sec24 53 93
IPR006900 Sec23/24_helical_dom 524 622
No external refs found!