YPR181C

Description : GTPase-activating protein, stimulates the GTPase activity of Sar1p; component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat, involved in ER to Golgi transport; substrate of Ubp3/Bre5 complex; ubiquitylated by Ub-ligase Rsp5p; proteasome-mediated degradation of Sec23p is regulated by Cdc48p [Source:SGD;Acc:S000006385]

Gene families : OG_03_0001625 (OF) Phylogenetic Tree(s): OG0001625_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YPR181C
Cluster	HCCA: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method
AFR97534	No alias	protein transporter SEC23;Sec23/Sec24 helical...	0.04	OF
AOA65775	No alias	Sec23/Sec24, helical domain	0.08	OF
AOA69531	No alias	Zinc finger, Sec23/Sec24-type	0.08	OF
CAG79640	No alias	Gelsolin-like domain	0.09	OF
CAK37008	No alias	Sec23/Sec24 beta-sandwich domain	0.12	OF
CBF89861	No alias	Protein transport protein sec23	0.1	OF
EAA32168	No alias	Sec23/Sec24 beta-sandwich	0.15	OF
EAL88052	No alias	protein transport protein Sec23, putative	0.07	OF
EAU89573	No alias	protein transporter SEC23	0.04	OF
EDN97626	No alias	Sec23/Sec24, trunk domain	0.07	OF
EGR45004	No alias	Sec23/Sec24 beta-sandwich	0.07	OF
EJF56800	No alias	Gelsolin repeat	0.03	OF
ESU07283	No alias	transporter SEC23	0.12	OF
KHC76645	No alias	protein transporter SEC23;Sec23/Sec24 helical...	0.18	OF
SPCC31H12.07.1	No alias	COPII cargo receptor subunit Sec23a (predicted)...	0.05	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006886	intracellular protein transport	IEA	Interproscan
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEA	Interproscan
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
BP	GO:0016192	vesicle-mediated transport	None	Extended
CC	GO:0030117	membrane coat	None	Extended
CC	GO:0030120	vesicle coat	None	Extended
CC	GO:0030127	COPII vesicle coat	IEA	Interproscan
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0048193	Golgi vesicle transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
CC	GO:0098796	membrane protein complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007123	Gelsolin-like_dom	637	724
IPR006896	Sec23/24_trunk_dom	120	388
IPR012990	Sec23_24_beta_S	399	510
IPR006895	Znf_Sec23_Sec24	53	93
IPR006900	Sec23/24_helical_dom	524	622

External Links

No external refs found!

YPR181C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation