Description : Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]
Gene families : OG_03_0002372 (OF) Phylogenetic Tree(s): OG0002372_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPR180W | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG80097 | No alias | THIF-type NAD/FAD binding fold | 0.03 | OF | |
EAU85910 | No alias | SUMO1 activating enzyme subunit | 0.03 | OF | |
ESA43421 | No alias | THIF-type NAD/FAD binding fold | 0.01 | OF | |
ESA43422 | No alias | THIF-type NAD/FAD binding fold | 0.01 | OF | |
ESU11536 | No alias | THIF-type NAD/FAD binding fold | 0.02 | OF | |
POV98554 | No alias | THIF-type NAD/FAD binding fold | 0.01 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008641 | ubiquitin-like modifier activating enzyme activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000594 | ThiF_NAD_FAD-bd | 16 | 331 |
No external refs found! |