Description : High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006256]
Gene families : OG_03_0000436 (OF) Phylogenetic Tree(s): OG0000436_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPR052C | |
Cluster | HCCA: Cluster_67 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR95829 | No alias | non-histone chromosomal protein 6;HMG (high mobility group) box | 0.08 | OF | |
CAG82043 | No alias | High mobility group box domain | 0.08 | OF | |
EAL92420 | No alias | nucleosome binding protein (Nhp6a), putative | 0.04 | OF | |
EJF59249 | No alias | HMG (high mobility group) box | 0.02 | OF | |
ESA43989 | No alias | High mobility group box domain | 0.04 | OF | |
ESA43990 | No alias | High mobility group box domain | 0.04 | OF | |
KHC70438 | No alias | hypothetical protein;HMG (high mobility group) box | 0.07 | OF | |
KHC78108 | No alias | non-histone chromosomal protein 6;HMG (high mobility group) box | 0.07 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR009071 | HMG_box_dom | 21 | 89 |
No external refs found! |