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YPR024W


Description : Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant [Source:SGD;Acc:S000006228]


Gene families : OG_03_0001565 (OF) Phylogenetic Tree(s): OG0001565_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YPR024W
Cluster HCCA: Cluster_33

Target Alias Description ECC score Gene Family Method Actions
CAG82601 No alias Peptidase M41 0.06 OF
CAK38759 No alias ATPase family associated with various cellular activities (AAA) 0.04 OF
CBF81608 No alias intermembrane space AAA protease IAP-1 0.02 OF
EAL89639 No alias intermembrane space AAA protease IAP-1 0.06 OF
EAU88544 No alias ATP-dependent peptidase 0.04 OF
EDO03609 No alias Peptidase M41 0.02 OF
EGR47931 No alias Peptidase M41 0.03 OF
KHC76643 No alias ATP-dependent metallopeptidase HflB;ATPase family... 0.03 OF
MGG_03926T0 No alias Cell division protease ftsH [Source:UniProtKB/TrEMBL;Acc:G4NH61] 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004222 metalloendopeptidase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006508 proteolysis IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR003959 ATPase_AAA_core 317 446
IPR041569 AAA_lid_3 470 512
IPR000642 Peptidase_M41 527 706
No external refs found!