YPL240C


Description : Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161]


Gene families : OG_03_0001080 (OF) Phylogenetic Tree(s): OG0001080_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YPL240C
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR95394 No alias cation-transporting ATPase;Histidine kinase-, DNA gyrase... 0.12 OF
AFR98377 No alias hsp90-like protein;Hsp90 protein;Histidine kinase-, DNA... 0.2 OF
AOA66179 No alias Heat shock protein Hsp90 family 0.28 OF
CAG81881 No alias Histidine kinase/HSP90-like ATPase 0.21 OF
CAK40452 No alias heat shock protein sspB-Aspergillus niger 0.11 OF
CBF74248 No alias heat shock protein 90 0.22 OF
EAA32062 No alias Heat shock protein Hsp90 family 0.16 OF
EAL85888 No alias molecular chaperone and allergen Mod-E/Hsp90/Hsp1 0.14 OF
EAU88255 No alias heat shock protein 90 0.13 OF
EDO04908 No alias Heat shock protein Hsp90 family 0.06 OF
EGR46340 No alias Histidine kinase/HSP90-like ATPase 0.1 OF
EJF61122 No alias Hsp90 protein 0.02 OF
ESU07397 No alias heat shock protein 90 0.14 OF
KHC71887 No alias molecular chaperone HtpG;Hsp90 protein;"Histidine... 0.31 OF
MGG_06759T0 No alias Heat shock protein 90 [Source:UniProtKB/TrEMBL;Acc:G4MLM8] 0.1 OF
POW03394 No alias Histidine kinase-, DNA gyrase B-, and HSP90-like... 0.03 OF
POW13974 No alias Histidine kinase/HSP90-like ATPase;Heat shock protein... 0.23 OF
SPAC926.04c.1 No alias Hsp90 chaperone [Source:PomBase;Acc:SPAC926.04c] 0.29 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006457 protein folding IEA Interproscan
MF GO:0051082 unfolded protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR003594 HATPase_C 26 180
IPR001404 Hsp90_fam 183 694
No external refs found!