Description : ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics [Source:SGD;Acc:S000006139]
Gene families : OG_03_0003142 (OF) Phylogenetic Tree(s): OG0003142_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPL218W | |
Cluster | HCCA: Cluster_67 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA66208 | No alias | Small GTPase superfamily, ARF/SAR type | 0.08 | OF | |
CAG82428 | No alias | Small GTPase superfamily, ARF/SAR type | 0.06 | OF | |
CBF89540 | No alias | Small COPII coat GTPase sar1 | 0.02 | OF | |
EAU88667 | No alias | small COPII coat GTPase | 0.02 | OF | |
EDO04837 | No alias | Small GTPase superfamily, ARF/SAR type | 0.03 | OF | |
EDO65417 | No alias | Small GTPase superfamily, ARF/SAR type | 0.06 | OF | |
ESU12763 | No alias | GTP-binding protein SAR1 | 0.08 | OF | |
KHC73362 | No alias | small COPII coat GTPase;ADP-ribosylation factor family | 0.09 | OF | |
MGG_06362T0 | No alias | Small COPII coat GTPase SAR1... | 0.05 | OF | |
POW16458 | No alias | Small GTPase superfamily, ARF/SAR type | 0.03 | OF | |
SPBC31F10.06c.1 | No alias | ADP-ribosylation factor Sar1 [Source:PomBase;Acc:SPBC31F10.06c] | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005525 | GTP binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR006689 | Small_GTPase_ARF/SAR | 11 | 190 |
No external refs found! |