YPL212C

Description : tRNA:pseudouridine synthase; introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; also acts on U2 snRNA; also pseudouridylates some mRNAs, and pseudouridylation level varies with growth phase; nuclear protein that appears to be involved in tRNA export; PUS1 has a paralog, PUS2, that arose from the whole genome duplication [Source:SGD;Acc:S000006133]

Gene families : OG_03_0001257 (OF) Phylogenetic Tree(s): OG0001257_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YPL212C
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AFR98591	No alias	tRNA pseudouridine(38-40) synthase;tRNA pseudouridine synthase	0.06	OF
AOA66403	No alias	Pseudouridine synthase I, TruA, alpha/beta domain	0.13	OF
CAG82083	No alias	Pseudouridine synthase I, TruA, alpha/beta domain	0.19	OF
CBF70055	No alias	tRNA pseudouridine synthase, putative	0.2	OF
EAL93142	No alias	tRNA pseudouridine synthase, putative	0.11	OF
EAU90525	No alias	pseudouridylate synthase	0.04	OF
EGR48689	No alias	Pseudouridine synthase I, TruA, alpha/beta domain	0.12	OF
ESU12695	No alias	tRNA pseudouridine synthase 1	0.15	OF
KHC73375	No alias	tRNA pseudouridine synthase 1	0.25	OF
MGG_07663T0	No alias	tRNA pseudouridine synthase 1...	0.1	OF
POW08534	No alias	Pseudouridine synthase I, TruA, alpha/beta domain	0.04	OF
SPCC126.03.1	No alias	tRNA pseudouridine synthase Lsp1 [Source:PomBase;Acc:SPCC126.03]	0.1	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009451	RNA modification	IEA	Interproscan
MF	GO:0009982	pseudouridine synthase activity	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016866	intramolecular transferase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR020097	PsdUridine_synth_TruA_a/b_dom	303	404

External Links

No external refs found!

YPL212C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation