Description : Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130]
Gene families : OG_03_0001097 (OF) Phylogenetic Tree(s): OG0001097_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPL209C | |
Cluster | HCCA: Cluster_66 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
POW14942 | No alias | Protein kinase domain | 0.02 | OF | |
SPCC320.13c.1 | No alias | aurora-B kinase Ark1 [Source:PomBase;Acc:SPCC320.13c] | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004672 | protein kinase activity | IEA | Interproscan |
MF | GO:0005524 | ATP binding | IEA | Interproscan |
BP | GO:0006468 | protein phosphorylation | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000719 | Prot_kinase_dom | 104 | 355 |
No external refs found! |