YPL120W


Description : Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy, Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has novel globular fold essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of higher eukaryote gene Beclin 1; human BECN1 can complement yeast null mutant [Source:SGD;Acc:S000006041]


Gene families : OG_03_0001638 (OF) Phylogenetic Tree(s): OG0001638_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YPL120W
Cluster HCCA: Cluster_68

Target Alias Description ECC score Gene Family Method Actions
AFR97976 No alias beclin 1;Apg6 BARA domain;Apg6 coiled-coil region 0.02 OF
SPAC20G8.10c.1 No alias autophagy associated beclin family protein Atg6... 0.02 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR040455 Atg6_BARA 317 535
IPR041691 Atg6/beclin_CC 180 314
No external refs found!