Description : Cytoplasmic NAD(+)-dependent protein deacetylase; deacetylation targets are primarily cytoplasmic proteins; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export [Source:SGD;Acc:S000005936]
Gene families : OG_03_0000341 (OF) Phylogenetic Tree(s): OG0000341_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YPL015C | |
Cluster | HCCA: Cluster_46 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0070403 | NAD+ binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR003000 | Sirtuin | 32 | 230 |
No external refs found! |