Description : Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]

Gene families : OG_03_0004078 (OF) Phylogenetic Tree(s): OG0004078_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR322C
Cluster HCCA: Cluster_48

Target Alias Description ECC score Gene Family Method Actions
CAK46660 No alias Arrestin_N terminal like 0.02 OF
SPAC1F12.05.1 No alias arrestin-related endocytic adaptor Any2 (predicted)... 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR024391 LDB19_N 144 346
No external refs found!