YOR124C

Description : Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; controls K63 homeostasis during oxidative stress; deubiquitinates Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity [Source:SGD;Acc:S000005650]

Gene families : OG_03_0001092 (OF) Phylogenetic Tree(s): OG0001092_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOR124C
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
AOA68323	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.04	OF
CAG80555	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.08	OF
CAK39206	No alias	A repeated domain in UCH-protein	0.05	OF
CBF81435	No alias	ubiquitin C-terminal hydrolase, putative	0.12	OF
EAA30689	No alias	UCH repeated domain	0.07	OF
EAL89067	No alias	ubiquitin C-terminal hydrolase, putative	0.12	OF
EDN95144	No alias	UCH repeated domain	0.04	OF
EGR48972	No alias	UCH repeated domain	0.07	OF
ESU12133	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.09	OF
KHC70464	No alias	ubiquitin carboxyl-terminal hydrolase 25/28;A repeated...	0.08	OF
MGG_00877T0	No alias	Putative uncharacterized protein...	0.05	OF
POW12650	No alias	UCH repeated domain;Peptidase C19, ubiquitin...	0.02	OF
SPAC328.06.1	No alias	ubiquitin C-terminal hydrolase Ubp2...	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016579	protein deubiquitination	IEA	Interproscan
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	Interproscan
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001394	Peptidase_C19_UCH	736	1255
IPR025305	UCH_repeat_domain	529	577
IPR025305	UCH_repeat_domain	658	719
IPR025305	UCH_repeat_domain	585	641

External Links

No external refs found!

YOR124C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation