YOR089C


Description : Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615]


Gene families : OG_03_0000375 (OF) Phylogenetic Tree(s): OG0000375_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YOR089C
Cluster HCCA: Cluster_64

Target Alias Description ECC score Gene Family Method Actions
EAA26716 No alias Small GTPase 0.02 OF
KHC84137 No alias small GTP-binding protein domain;Ras family 0.04 OF

Type GO Term Name Evidence Source
MF GO:0003924 GTPase activity IEA Interproscan
MF GO:0005525 GTP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001806 Small_GTPase 9 171
No external refs found!