YOR086C


Description : Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication [Source:SGD;Acc:S000005612]


Gene families : OG_03_0000772 (OF) Phylogenetic Tree(s): OG0000772_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YOR086C
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
AFR98020 No alias transmembrane protein;C2 domain 0.03 OF
AGV14731 No alias transmembrane protein;C2 domain 0.03 OF
AOA66178 No alias C2 domain 0.04 OF
KHC83091 No alias hypothetical protein;C2 domain 0.06 OF
KHC83812 No alias hypothetical protein;C2 domain 0.07 OF
MGG_09947T0 No alias Tricalbin-1 [Source:UniProtKB/TrEMBL;Acc:G4MRL6] 0.03 OF
POW17974 No alias C2 domain 0.03 OF
SPAPYUK71.03c.1 No alias synaptotagmin family C2 domain protein, Syn1... 0.03 OF
YNL087W No alias ER protein involved in ER-plasma membrane tethering; one... 0.04 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000008 C2_dom 535 621
IPR000008 C2_dom 386 482
IPR000008 C2_dom 992 1085
IPR000008 C2_dom 659 754
No external refs found!