Description : 5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication [Source:SGD;Acc:S000005559]

Gene families : OG_03_0001327 (OF) Phylogenetic Tree(s): OG0001327_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOR033C
Cluster HCCA: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
AFR93007 No alias exonuclease 1;XPG I-region;XPG N-terminal domain 0.02 OF
CAK46789 No alias XPG I-region 0.03 OF
CBF83526 No alias 5'-3' exonuclease and flap-endonuclease 0.04 OF
EAL92675 No alias exonuclease, putative 0.04 OF
EGR48992 No alias XPG-I domain 0.04 OF
POV94766 No alias XPG N-terminal 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004518 nuclease activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006085 XPG_DNA_repair_N 1 98
IPR006086 XPG-I_dom 139 227
No external refs found!