YOR025W

Description : Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000005551]

Gene families : OG_03_0000633 (OF) Phylogenetic Tree(s): OG0000633_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YOR025W
Cluster	HCCA: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method
AOA67531	No alias	Sirtuin family	0.11	OF
EDO01206	No alias	Sirtuin family	0.02	OF
KHC75039	No alias	hypothetical protein;Sir2 family	0.11	OF
MGG_04588T0	No alias	Sir2 family histone deacetylase Hst4...	0.02	OF
SPAC1783.04c.1	No alias	Sirtuin family histone deacetylase Hst4...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	None	Extended
MF	GO:0070403	NAD+ binding	IEA	Interproscan
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR003000	Sirtuin	60	287

External Links

No external refs found!

YOR025W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation