KHC73248

Description : DNA topoisomerase 1;"Eukaryotic DNA topoisomerase I, DNA binding fragment";"Eukaryotic DNA topoisomerase I, catalytic core";C-terminal topoisomerase domain

Gene families : OG_03_0002666 (OF) Phylogenetic Tree(s): OG0002666_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: KHC73248
Cluster	HCCA: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method
CAG81506	No alias	Topoisomerase I C-terminal domain	0.03	OF
CAK36999	No alias	Eukaryotic DNA topoisomerase I, catalytic core	0.03	OF
EJF57661	No alias	Eukaryotic DNA topoisomerase I, DNA binding fragment	0.03	OF
ESA44117	No alias	DNA topoisomerase I, catalytic core, eukaryotic-type	0.03	OF
MGG_09917T0	No alias	DNA topoisomerase 1 [Source:UniProtKB/TrEMBL;Acc:G4MR71]	0.02	OF
SPBC1703.14c.1	No alias	DNA topoisomerase I [Source:PomBase;Acc:SPBC1703.14c]	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR008336	TopoI_DNA-bd_euk	157	372
IPR013500	TopoI_cat_euk	376	602
IPR025834	TopoI_C_dom	711	780

External Links

No external refs found!

KHC73248

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation