YOL068C

Description : NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005429]

Gene families : OG_03_0000341 (OF) Phylogenetic Tree(s): OG0000341_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YOL068C
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method	Actions
MGG_02488T0	No alias	NAD-dependent histone deacetylase SIR2...	0.02	OF
POV99994	No alias	Sirtuin family	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	None	Extended
MF	GO:0070403	NAD+ binding	IEA	Interproscan
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007654	NAD-dep_histone_deAcase_SIR2_N	49	207
IPR003000	Sirtuin	208	419

External Links

No external refs found!

YOL068C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation