Description : NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005429]

Gene families : OG_03_0000341 (OF) Phylogenetic Tree(s): OG0000341_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YOL068C
Cluster HCCA: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
MGG_02488T0 No alias NAD-dependent histone deacetylase SIR2... 0.02 OF
POV99994 No alias Sirtuin family 0.02 OF

Type GO Term Name Evidence Source
MF GO:0070403 NAD+ binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007654 NAD-dep_histone_deAcase_SIR2_N 49 207
IPR003000 Sirtuin 208 419
No external refs found!