Description : Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals [Source:SGD;Acc:S000005423]
Gene families : OG_03_0000311 (OF) Phylogenetic Tree(s): OG0000311_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YOL062C | |
Cluster | HCCA: Cluster_46 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96538 | No alias | AP-1 complex subunit mu-1;Adaptor complexes medium... | 0.03 | OF | |
CAG82072 | No alias | Mu homology domain | 0.03 | OF | |
CBF78005 | No alias | hypothetical protein similar to clathrin associated protein AP47 | 0.02 | OF | |
CBF80011 | No alias | AP-2 adaptor complex subunit mu, putative | 0.04 | OF | |
EAA31384 | No alias | Mu homology domain | 0.02 | OF | |
EDO01306 | No alias | Mu homology domain | 0.02 | OF | |
EDO05038 | No alias | Mu homology domain | 0.02 | OF | |
EFI27469 | No alias | clathrin assembly protein AP47 | 0.03 | OF | |
EJF59668 | No alias | Clathrin adaptor complex small chain | 0.02 | OF | |
ESU07495 | No alias | AP-2 complex subunit mu-1 | 0.03 | OF | |
MGG_10633T0 | No alias | AP-1 complex subunit mu-1 [Source:UniProtKB/TrEMBL;Acc:G4MQC8] | 0.02 | OF | |
POV93904 | No alias | Mu homology domain | 0.02 | OF | |
POW00520 | No alias | Mu homology domain | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR028565 | MHD | 198 | 490 |
No external refs found! |