Description : Acetyl-CoA carboxylase, biotin containing enzyme; catalyzes carboxylation of cytosolic acetyl-CoA to form malonyl-CoA and regulates histone acetylation by regulating the availablity of acetyl-CoA; required for de novo biosynthesis of long-chain fatty acids; ACC1 has a paralog, HFA1, that arose from the whole genome duplication [Source:SGD;Acc:S000005299]
Gene families : OG_03_0001879 (OF) Phylogenetic Tree(s): OG0001879_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YNR016C | |
| Cluster | HCCA: Cluster_4 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR96079 | No alias | acetyl-CoA carboxylase/biotin... | 0.06 | OF | |
| AOA65544 | No alias | Acetyl-CoA carboxylase | 0.07 | OF | |
| AOA65545 | No alias | Acetyl-CoA carboxylase | 0.06 | OF | |
| CAG82031 | No alias | Biotin/lipoyl attachment | 0.04 | OF | |
| CBF70132 | No alias | Acetyl-CoA carboxylasePutative uncharacterized protein... | 0.05 | OF | |
| EAA33781 | No alias | Biotin carboxylase, C-terminal | 0.04 | OF | |
| EAL93163 | No alias | acetyl-CoA carboxylase | 0.05 | OF | |
| EFI27362 | No alias | acetyl CoA carboxylase | 0.03 | OF | |
| EGR45699 | No alias | Acetyl-CoA carboxylase, central domain | 0.05 | OF | |
| ESU12689 | No alias | acetyl-CoA carboxylase | 0.04 | OF | |
| KHC71046 | No alias | acetyl-CoA carboxylase/biotin carboxylase;Biotin... | 0.07 | OF | |
| MGG_07613T0 | No alias | Acetyl-CoA carboxylase [Source:UniProtKB/TrEMBL;Acc:G4N2L8] | 0.04 | OF | |
| POV99067 | No alias | Biotin/lipoyl attachment;Biotin carboxylase-like,... | 0.02 | OF | |
| SPAC56E4.04c.1 | No alias | acetyl-CoA/biotin carboxylase [Source:PomBase;Acc:SPAC56E4.04c] | 0.08 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003989 | acetyl-CoA carboxylase activity | IEA | Interproscan |
| MF | GO:0005524 | ATP binding | IEA | Interproscan |
| BP | GO:0006633 | fatty acid biosynthetic process | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| No external refs found! |