YNL293W


Description : Rab GTPase-activating protein; regulates endocytosis via inactivation of Vps21p at endosomes and vacuole fusion via inactivation of Ypt7p at vacuoles; also acts on Ypt52p and Sec4p; localizes to plasma membrane, sites of polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; similar to TBC-domain Tre2 oncogene; MSB3 has a paralog, MSB4, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null [Source:SGD;Acc:S000005237]


Gene families : OG_03_0003902 (OF) Phylogenetic Tree(s): OG0003902_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YNL293W
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
EAA27689 No alias Rab-GTPase-TBC domain 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000195 Rab-GTPase-TBC_dom 425 474
IPR000195 Rab-GTPase-TBC_dom 227 388
No external refs found!