YNL281W


Description : Heat shock protein regulator; binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; role in regulating Hsp90 inhibitor drug sensitivity; GFP-fusion protein localizes to the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005225]


Gene families : OG_03_0001980 (OF) Phylogenetic Tree(s): OG0001980_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YNL281W
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR92439 No alias chaperone activator;Activator of Hsp90 ATPase,... 0.09 OF
AGV15293 No alias chaperone activator;Activator of Hsp90 ATPase,... 0.1 OF
AOA65497 No alias Activator of Hsp90 ATPase, N-terminal 0.11 OF
CAG83201 No alias Activator of Hsp90 ATPase, N-terminal 0.08 OF
CAK38789 No alias Activator of Hsp90 ATPase homolog 1-like protein 0.1 OF
CBF81583 No alias co-chaperone 0.1 OF
EAA26847 No alias Activator of Hsp90 ATPase homologue 1-like 0.05 OF
EAL89658 No alias Aha1 domain family 0.05 OF
EAU88891 No alias chaperone activator 0.04 OF
EGR46850 No alias Activator of Hsp90 ATPase homologue 1-like 0.05 OF
ESU16134 No alias Activator of Hsp90 ATPase, N-terminal 0.08 OF
KHC69760 No alias hypothetical protein;Activator of Hsp90 ATPase homolog... 0.08 OF
KHC73327 No alias hypothetical protein;"Activator of Hsp90 ATPase, N-terminal" 0.08 OF
POW10600 No alias Activator of Hsp90 ATPase, N-terminal;Activator of Hsp90... 0.17 OF
SPBC1711.08.1 No alias chaperone activator Aha1 (predicted)... 0.1 OF

Type GO Term Name Evidence Source
MF GO:0001671 ATPase activator activity IEA Interproscan
MF GO:0051087 chaperone binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR015310 AHSA1_N 13 147
No external refs found!