Description : Catalytic subunit of DNA polymerase (II) epsilon; a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; participates in leading-strand synthesis during DNA replication; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p [Source:SGD;Acc:S000005206]
Gene families : OG_03_0004099 (OF) Phylogenetic Tree(s): OG0004099_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YNL262W | |
Cluster | HCCA: Cluster_41 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94037 | No alias | DNA polymerase epsilon catalytic subunit A;DNA... | 0.09 | OF | |
AOA66508 | No alias | DNA-directed DNA polymerase, family B, exonuclease domain | 0.14 | OF | |
CAG80023 | No alias | DNA-directed DNA polymerase, family B, multifunctional domain | 0.18 | OF | |
CAK48615 | No alias | Domain of unknown function (DUF1744) | 0.09 | OF | |
CBF83469 | No alias | DNA polymerase epsilon catalytic subunit A | 0.11 | OF | |
EAA26703 | No alias | DNA-directed DNA polymerase, family B, exonuclease domain | 0.13 | OF | |
EAL92625 | No alias | DNA polymerase epsilon, catalytic subunit A/POL2, putative | 0.22 | OF | |
EAU86784 | No alias | DNA polymerase epsilon catalytic subunit A | 0.05 | OF | |
EGR49185 | No alias | DNA-directed DNA polymerase, family B, multifunctional domain | 0.22 | OF | |
ESU12111 | No alias | DNA polymerase epsilon | 0.05 | OF | |
KHC70552 | No alias | DNA polymerase epsilon catalytic subunit A;Domain of... | 0.23 | OF | |
MGG_03850T0 | No alias | DNA polymerase epsilon catalytic subunit A... | 0.11 | OF | |
SPBC25H2.13c.1 | No alias | DNA polymerase epsilon catalytic subunit Pol2... | 0.15 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEA | Interproscan |
MF | GO:0003677 | DNA binding | IEA | Interproscan |
MF | GO:0003887 | DNA-directed DNA polymerase activity | IEA | Interproscan |
CC | GO:0005634 | nucleus | IEA | Interproscan |
BP | GO:0006260 | DNA replication | IEA | Interproscan |
MF | GO:0008270 | zinc ion binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |