Description : Cytosolic copper metallochaperone; transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake; human homolog ATOX1 can complement yeast atx1 mutant; overexpression of human ATOX1 suppresses lysine auxotrophy of the yeast sod1 null mutant, as does overexpression of yeast ATX1 [Source:SGD;Acc:S000005203]
Gene families : OG_03_0003003 (OF) Phylogenetic Tree(s): OG0003003_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YNL259C | |
Cluster | HCCA: Cluster_67 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
ESU17913 | No alias | Heavy metal-associated domain, HMA | 0.03 | OF | |
POW13922 | No alias | Heavy metal-associated domain, HMA | 0.03 | OF | |
SPBC1709.10c.1 | No alias | copper chaperone Atx1 [Source:PomBase;Acc:SPBC1709.10c] | 0.07 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0030001 | metal ion transport | IEA | Interproscan |
MF | GO:0046872 | metal ion binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR006121 | HMA_dom | 9 | 66 |
No external refs found! |