Description : Glucose-6-phosphate dehydrogenase (G6PD); catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidative stress; protein abundance increases in response to DNA replication stress; homolog of human G6PD which is deficient in patients with hemolytic anemia; human G6PD can complement yeast zwf1 null mutant [Source:SGD;Acc:S000005185]

Gene families : OG_03_0002645 (OF) Phylogenetic Tree(s): OG0002645_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YNL241C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AOA66946 No alias Glucose-6-phosphate dehydrogenase, C-terminal 0.06 OF
CAG79872 No alias Glucose-6-phosphate dehydrogenase, NAD-binding 0.02 OF
EGR50815 No alias Glucose-6-phosphate dehydrogenase, NAD-binding 0.02 OF
KHC83645 No alias glucose-6-phosphate 1-dehydrogenase;"Glucose-6-phosphate... 0.1 OF
SPAC3A12.18.1 No alias glucose-6-phosphate 1-dehydrogenase (predicted)... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEA Interproscan
BP GO:0006006 glucose metabolic process IEA Interproscan
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA Interproscan
MF GO:0050661 NADP binding IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR022674 G6P_DH_NAD-bd 16 196
IPR022675 G6P_DH_C 198 484
No external refs found!