Description : Glucose-6-phosphate dehydrogenase (G6PD); catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidative stress; protein abundance increases in response to DNA replication stress; homolog of human G6PD which is deficient in patients with hemolytic anemia; human G6PD can complement yeast zwf1 null mutant [Source:SGD;Acc:S000005185]
Gene families : OG_03_0002645 (OF) Phylogenetic Tree(s): OG0002645_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YNL241C | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA66946 | No alias | Glucose-6-phosphate dehydrogenase, C-terminal | 0.06 | OF | |
CAG79872 | No alias | Glucose-6-phosphate dehydrogenase, NAD-binding | 0.02 | OF | |
EGR50815 | No alias | Glucose-6-phosphate dehydrogenase, NAD-binding | 0.02 | OF | |
KHC83645 | No alias | glucose-6-phosphate 1-dehydrogenase;"Glucose-6-phosphate... | 0.1 | OF | |
SPAC3A12.18.1 | No alias | glucose-6-phosphate 1-dehydrogenase (predicted)... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004345 | glucose-6-phosphate dehydrogenase activity | IEA | Interproscan |
BP | GO:0006006 | glucose metabolic process | IEA | Interproscan |
MF | GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | IEA | Interproscan |
MF | GO:0050661 | NADP binding | IEA | Interproscan |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |