YNL216W

Description : Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; relocalizes to cytosol under hypoxia; conserved protein with N-terminal BRCT domain, central region with homology to Myb DNA binding domain, and C-terminal Rap1-specific protein-interaction domain (RCT domain); recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters [Source:SGD;Acc:S000005160]

Gene families : OG_03_0008491 (OF) Phylogenetic Tree(s): OG0008491_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YNL216W
Cluster	HCCA: Cluster_37

Target	Alias	Description	ECC score	Gene Family Method	Actions
AOA67001	No alias	TRF2-interacting telomeric protein/Rap1, C-terminal	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR015280	Rap1_DNA-bd	448	579
IPR001357	BRCT_dom	127	207
IPR001005	SANT/Myb	362	411
IPR021661	Rap1_C	742	823

External Links

No external refs found!

YNL216W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation