YBR218C


Description : Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication [Source:SGD;Acc:S000000422]


Gene families : OG_03_0000155 (OF) Phylogenetic Tree(s): OG0000155_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YBR218C
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
AFR96227 No alias pyruvate carboxylase;Carbamoyl-phosphate synthase L... 0.05 OF
CBF77471 No alias pyruvate carboxylase 0.02 OF
EAA36400 No alias Biotin carboxylase, C-terminal 0.05 OF
EAL90016 No alias pyruvate carboxylase, putative 0.19 OF
ESU13268 No alias pyruvate carboxylase 0.04 OF
KHC76480 No alias pyruvate carboxylase;Conserved carboxylase... 0.12 OF
KHC77660 No alias pyruvate carboxylase;Conserved carboxylase... 0.12 OF
SPBC17G9.11c.1 No alias pyruvate carboxylase Pyr1 [Source:PomBase;Acc:SPBC17G9.11c] 0.1 OF

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005482 Biotin_COase_C 360 467
IPR003379 Carboxylase_cons_dom 852 1052
IPR000891 PYR_CT 560 828
IPR005479 CbamoylP_synth_lsu-like_ATP-bd 136 344
IPR005481 BC-like_N 21 131
IPR000089 Biotin_lipoyl 1102 1169
No external refs found!